2-atsilgliserin-3-fosfat O-atsiltransferaza

Enzimologiyada 2-atsilgliserol-3-fosfat O-atsiltransferaza (EC)) kimyoviy reaksiyani katalizlovchi ferment hisoblanadi.

asil-CoA + 2-atsil-sn-gliserin 3-fosfat $\rightleftharpoons$ CoA + 1,2-diasil-sn-glitserin 3-fosfat

Shunday qilib, bu fermentning ikkita substrati asil-CoA va 2-atsil-sn-glitserin 3-fosfat, uning ikkita oxirgi mahsuloti esa CoA va 1,2-diasil-sn-gliserol 3-fosfat hisoblanadi.

Ushbu ferment transferazlar oilasiga, xususan, aminoatsil guruhlardan boshqa guruhlarni oʻtkazuvchi asiltransferazalarga tegishli. Ushbu ferment sinfining sistematik nomi asil-CoA: 2-atsil-sn-glitserin 3-fosfat O-atsiltransferaza boʻlib, bu ferment 2-atsilgliserofosfat asiltransferaza deb ham ataladi. Bu ferment glitserofosfolipid metabolizmida ishtirok etadi.

Manbalar

• "Acyl-donor specificities of partially purified 1-acylglycerophosphate acyltransferase, 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes". Eur. J. Biochem. 38 (1): 25–31. 1973. doi:10.1111/j.1432-1033.1973.tb03028.x. PMID 4774123.