Fayl:Serpin mechanism.png
Bu prevyuning hajmi: 725 × 599 piksel. Boshqa oʻlchamlari: 290 × 240 piksel | 581 × 480 piksel | 929 × 768 piksel | 1 239 × 1 024 piksel | 1 800 × 1 488 piksel.
Asl fayl (1 800 × 1 488 piksel, fayl hajmi: 513 KB, MIME tipi: image/png)
Qisqa izoh
| Taʼrif |
English: Serine proteases operate by a two-step catalytic mechanism. First, the substrate (blue) is attacked by the catalytic triad (red) to form an acyl-enzyme intermediate. The intermediate is typically resolved by hydrolysis by water. However, when the reactive centre loop (RCL) of a serpin is attacked, the conformational change (blue arrow) pulls the catalytic triad out of position, preventing it from completing catalysis. (Based on PDB: 1K9O, 1EZX) |
| Sanasi | |
| Manba | Oʻzimning ishim |
| Muallif | Thomas Shafee |
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I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution 4.0 International license.
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- atribut – Siz tegishli litsenziyaga havolani taqdim etishingiz va oʻzgartirishlar kiritilganligini koʻrsatishingiz kerak. Siz buni har qanday oqilona yoʻl bilan qilishingiz mumkin, lekin litsenziar Sizni yoki Sizning foydalanishingizni ma'qullashini taklif qiladigan tarzda emas.
Fayl tarixi
Faylning biror paytdagi holatini koʻrish uchun tegishli sana/vaqtga bosingiz.
| Sana/Vaqt | Miniatura | Oʻlchamlari | Foydalanuvchi | Izoh | |
|---|---|---|---|---|---|
| joriy | 09:56, 22-Dekabr 2015 | | 1 800 × 1 488 (513 KB) | Evolution and evolvability | Higher resolution |
| 05:19, 19-Dekabr 2015 |  | 1 362 × 1 126 (300 KB) | Evolution and evolvability | Minor arrow correction | |
| 05:08, 19-Dekabr 2015 |  | 1 362 × 1 126 (300 KB) | Evolution and evolvability | added arrow and removed transparency | |
| 05:04, 19-Dekabr 2015 |  | 1 362 × 1 114 (360 KB) | Evolution and evolvability | Cross-wiki upload from en.wikipedia.org |
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